Dermoscopy examination of petechial lesions in a patient with Dermatitis Herpetiformis

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Dermoscopy examination of petechial lesions in a patient with Dermatitis Herpetiformis*

An uncommon skin manifestation of Dermatitis Herpetiformis is palmar and plantar purpura. Dermoscopic examination is useful for any skin condition since it allows recognition of structures that are not discernible to the naked eye. A 22 year-old Caucasian man was admitted with excoriated lesions and pruritus. Petechial lesions could be seen on volar aspect of the digits on the hands and feet. D...

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Dermatitis herpetiformis.

Dermatitis herpetiformis (DH) is an autoimmune, pleiomorphic, papulovesicular disorder associated with celiac disease and gluten sensitivity. DH is characterized by subepidermal bullae on hematoxylin and eosin staining and granular immunoglobulin A deposits in the dermal papillae using the direct immunofluorescence method. Antibodies to tissue transglutaminase and epidermal transgulatminase can...

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Gene Expression Profiling in Dermatitis Herpetiformis Skin Lesions

Dermatitis herpetiformis (DH) is an autoimmune blistering skin disease associated with gluten-sensitive enteropathy (CD). In order to investigate the pathogenesis of skin lesions at molecular level, we analysed the gene expression profiles in skin biopsies from 6 CD patients with DH and 6 healthy controls using Affymetrix HG-U133A 2.0 arrays. 486 genes were differentially expressed in DH skin c...

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Dermatitis herpetiformis.

Dermatitis herpetiformis (DH), described over 100 years ago, is a life-long blistering skin disease that can appear at any age. Dapsone controls the rash effectively and has been used for over 50 years in the treatment of DH. Major landmark in the research of DH was 30 years ago the discovery of granular IgA deposits in the upper papillary dermis,1 and further differentiation of an autoimmune d...

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ژورنال

عنوان ژورنال: Anais Brasileiros de Dermatologia

سال: 2013

ISSN: 0365-0596

DOI: 10.1590/abd1806-4841.20132089